Table 1.
Clinical characteristics of subjects in this study
| Healthy individuals | CHB patients | Cirrhosis patients | HCC patients | ||
|---|---|---|---|---|---|
| Number of subjects | 104 | 105 | 58 | 48 | |
| Age | (year, ranger) | 25-64 | 17-63 | 29-76 | 33-78 |
| (year, mean) | 39.3 | 37.2 | 49.3 | 51.5 | |
| Sex (male:female) | 58:46 | 64:41 | 40:18 | 36:12 | |
| HBsAg positive | No | Yes | Yes | Yes | |
| NOX 2 (mean ± SD) pg/ml | 930.64 ± 474.10 | 2944.10 ± 1078.74 | 3605.63 ± 857.92 | 4482.48 ± 1086.98 | |
| SOD (mean ± SD) U/ml | 168.1 ± 16.9 | 137.5 ± 31.0 | 135.8 ± 33.6 | 122.7 ± 33.8 | |
| IL-6 (mean ± SD) pg/ml | 1.69 ± 0.54 | 4.06 ± 1.48 | 16.98 ± 4.65 | 22.48 ± 7.19 | |
| ISG15 (mean ± SD) ng/m | 3.21 ± 0.93 | 6.74 ± 2.88 | 15.93 ± 5.30 | 9.21 ± 2.99 | |
| ALP (mean ± SD) U/L | 69.0 ± 17.0 | 94.2 ± 46.7 | 128.8 ± 43.6 | 210.2 ± 119.0 | |
| GGT (mean ± SD) U/L | 23.1 ± 13.3 | 58.5 ± 87.0 | 132.9 ± 71.7 | 188.9 ± 150.4 | |
| ALT (mean ± SD) U/L | 24.0 ± 14.3 | 118.7 ± 244.9 | 248.1 ± 361.9 | 93.5 ± 89.7 | |
| AST (mean ± SD) U/L | 24.1 ± 4.9 | 79.5 ± 117.8 | 240.66 ± 293.4 | 98.1 ± 103.1 | |
| HBV DNA (mean ± SD) copies/ml | - | 10242588 ± 24242785 | 2837049 ± 6971344 | 846385 ± 1833953 | |