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. 2018 Aug 15;10(8):2491–2501.

Figure 5.

Figure 5

AD regulates IRS1-PI3K/AKT pathway to protect kidney function. Data are representative images for IRS1, phospho-IRS1Y896, phospho-IRY1361, phospho-IRS1S636/639, PI3K, phospho-PI3K, AKT, phospho-AKTT308, phospho-AKTS473. A. Effects of HD on the expression of IRS1, phospho-IRS1307IRS1Y896, phospho--IRY1361, phospho-IRS1S636/639. B. Protein expression is shown relative to β-actin. C. Effect of HD on the expression of PI3K, phospho-PI3K, AKT, phospho-AKTT308, phospho-AKTS473. D. Protein expression is shown relative to β-actin. **P < 0.001, compared with db/m group; ##P < 0.001, #P < 0.05, compared with db/db group (n = 10).