Table 2.

Univariate and multivariate logistic regression model analyses with BRAF mutation

Parameters	Univerlate analysis		Multivariate analysis
	Hazard ratio (95% CI)	P value	Hazard ratio (95% CI)	P value
Age (years)
< 45 vs ≥ 45	5.458 (0.989-30.125)	0.052
Gender
Male vs Female	1.242 (0.328-4.710)	0.75
Type of surgery
Right resection vs Left and total resection	1.669 (0.638-4.365)	0.296
Tumor size (mm)
< 10 vs ≥ 10	0.970 (0.269-3.504)	0.963
Tumor focus
Unifocal vs Multifocal	0.506 (0.096-2.658)	0.421
Lymph node metastasis
Yes vs No	0.343 (0.041-2.868)	0.323
Pathological TNM classification
T stage
T1 vs T2+T3	1.271 (0.211-7.660)	0.793
N stage
N0 vs N1a+N1b	0.548 (0.117-2.572)	0.446
TNM stage
I+II vs III+VIa	0.533 (0.292-0.972)	0.04	0.503 (0.266-0.951)	0.035
White blood cell (W)
< 5.82 vs ≥ 5.82	0.155 (0.022-1.087)	0.061
Hemoglobin (Hb)
< 137 vs ≥ 137	0.979 (0.247-3.885)	0.976
Neutrophils (N)
< 3.30 vs ≥ 3.30	6.646 (0.790-55.880)	0.081
Monocyte (M)
< 0.30 vs ≥ 0.30	3.426 (1.158-10.135)	0.026	4.056 (1.268-12.973)	0.018
Platelet (P)
< 221 vs ≥ 221	2.028 (0.559-7.354)	0.282
Lymphocyte (L)
< 1.90 vs ≥ 1.90	1.991 (0.482-8.226)	0.341
SIRI
< 0.43 vs ≥ 0.43	2.206 (0.884-5.503)	0.033	2.574 (1.005-6.590)	0.049
Ki-67
Positive vs Negative	0.588 (0.143-2.425)	0.463
P53
Positive vs Negative	0.598 (0.182-1.967)	0.398
CK19
Positive vs Negative	1.742 (0.467-6.494)	0.408
Galectin-3
Positive vs Negative	4.583 (1.294-16.233)	0.018	7.116 (1.598-31.699)	0.010
CD56
Positive vs Negative	0.624 (0.156-2.497)	0.505