Figure 4.

POLP inhibited the expression of NF-κBp65, magnification ×400. A. Immunohistochemistry result of control group with expressing NF-κBp65 barely. B. The expression level of NF-κBp65 increased sharply with crypts and goblet cells disappeared. C. Immunohistochemistry result of sulfasalazine control. D. Immunohistochemistry result of POLP with a concentration of 0.5 g/mL. E. The column heights represented the positively stained cell rates. F. The results of RT-qPCR. The column heights represented the mRNA level of NF-κBp65. Error bars represented means ± SEM of n=3, *P<0.05 and **P<0.01 compared with colitis.