5.

Differences in texture features in GLCM category between each pair of groups of preinvasive lesions, MIAs and IPAs

Texture features	P value
	Preinvasive lesions vs. MIAs	Preinvasive lesions vs. IPAs	MIAs vs. IPAs
GLCM, gray-level co-occurrence matrix; MIAs, minimally invasive adenocarcinomas; IPAs, invasive pulmonary adenocarcinomas; IMC1, informational measure of correlation 1; IDMN, inverse difference moment normalized; IDN, inverse difference normalized. P value was calculated with Kruskal-Wallis rank sum test followed by Dunn-Bonferroni post hoc test.
Autocorrelation	>0.05	<0.001	<0.001
Cluster prominence	>0.05	<0.001	<0.001
Cluster shade	>0.05	<0.001	<0.001
Cluster tendency	>0.05	<0.001	<0.001
Contrast	>0.05	<0.001	<0.001
Correlation	0.019	>0.05	<0.05
Difference entropy	>0.05	0.003	<0.001
Dissimilarity	>0.05	<0.001	<0.001
Homogeneity 1	>0.05	0.006	<0.001
Homogeneity 2	>0.05	0.005	<0.001
IMC1	>0.05	0.017	0.001
IDMN	>0.05	0.001	<0.001
IDN	>0.05	0.001	<0.001
Inverse variance	>0.05	0.020	<0.001
Maximum probability	>0.05	<0.001	<0.001
Sum average	>0.05	<0.001	<0.001
Sum entropy	>0.05	0.005	<0.001
Sum variance	>0.05	0.001	<0.001
Energy (GLCM)	>0.05	0.001	<0.001
Entropy (GLCM)	>0.05	0.004	<0.001
Variance (GLCM)	>0.05	<0.001	<0.001