8.

Logistic regression analyses of texture features between each pair of groups of preinvasive lesions, MIAs and IPAs

Features	Regression coefficients	P	OR	95% CI
MIAs, minimally invasive adenocarcinomas; IPAs, invasive pulmonary adenocarcinomas; OR, odds ratio; 95% CI, 95% confidence interval; *, univariate logistic regression analysis; #, multiple logistic regression analysis entered with significant features (P<0.05) in univariable model. For univariate and multiple logistic regression analyses, the independent variable was each feature and the dependent variable was each group.
Group of preinvasive lesions & Group of MIAs
Correlation*	0.577	0.046	1.781	1.052−3.363
Group of preinvasive lesions & Group of IPAs
Voxel count*	1.075	<0.001	2.930	1.704−5.451
Group of MIAs & Group of IPAs
Surface area (mm2)#	0.451	0.040	1.571	1.033−2.494
Extruded surface area#	−1.073	0.013	0.341	0.133−0.758