S2.
Interobserver agreement regarding texture features of GGO ROIs using interclass ICC
| Texture features | ICC (95% CI) | Texture features | ICC (95% CI) |
| GGO, ground-glass opacity lesions; ROI, region of interest; ICC, correlation coefficient analysis; Volume cc, volume in cubic centimeters; LRLGLE, long run low gray level emphasis; SRE, short run emphasis; 95% CI, 95% confidence interval; IMC1, informational measure of correlation 1; IDMN, inverse difference moment normalized; IDN, inverse difference normalized; GLCM, gray-level co-occurrence matrix; RLN, run length nonuniformity; RP, run percentage; LGLRE, low gray level run emphasis; HGLRE, high gray level run emphasis; SRLGLE, short run low gray level emphasis; SRHGLE, short run high gray level emphasis; LRHGLE, long run high gray level emphasis; LRE, long run emphasis; GLN, gray level nonuniformity. | |||
| Gray levels | 0.908 (0.100–0.981) | Autocorrelation | 0.997 (0.261–0.999) |
| Voxel count | 0.999 (0.595–1.000) | Cluster prominence | 0.908 (0.010–0.981) |
| Energy | 0.714 (0.002–0.928) | Cluster shade | 0.948 (0.018–0.989) |
| Entropy | 0.838 (0.005–0.964) | Cluster tendency | 0.512 (0.001–0.844) |
| Minimum intensity | 0.417 (0.001–0.787) | Contrast | 0.851 (0.006–0.967) |
| Maximum intensity | 0.999 (0.650–1.000) | Correlation | 0.829 (0.005–0.962) |
| Mean intensity | 0.834 (0.005–0.963) | Difference entropy | 0.999 (0.641–1.000) |
| Median intensity | 0.984 (0.056–0.997) | Dissimilarity | 0.998 (0.362–1.000) |
| Range | 0.968 (0.029–0.994) | Homogeneity 1 | 0.992 (0.110–0.998) |
| Mean deviation | 0.556 (0.001–0.866) | Homogeneity 2 | 0.998 (0.393–1.000) |
| Root mean square | 0.721 (0.003–0.930) | IMC1 | 0.829 (0.005–0.962) |
| Standard deviation | 0.707 (0.002–0.926) | IDMN | 0.832 (0.005–0.962) |
| Skewness | 0.952 (0.019–0.990) | IDN | 0.997 (0.221–0.999) |
| Kurtosis | 0.741 (0.003–0.937) | Inverse variance | 0.996 (0.215–0.999) |
| Variance | 0.998 (0.367–1.000) | Maximum probability | 0.999 (0.425–1.000) |
| Uniformity | 0.910 (0.010–0.981) | Sum average | 0.999 (0.564–1.000) |
| Volume (mm3) | 0.999 (0.472–1.000) | Sum entropy | 0.996 (0.198–0.999) |
| Surface area (mm2) | 0.994 (0.150–0.999) | Sum variance | 0.886 (0.008–0.976) |
| Surface: volume ratio | 0.999 (0.537–1.000) | Energy (GLCM) | 0.999 (0.596–1.000) |
| Compactness 1 | 0.807 (0.004–0.956) | Entropy (GLCM) | 0.998 (0.354–1.000) |
| Compactness 2 | 0.999 (0.602–1.000) | Variance (GLCM) | 0.965 (0.027–0.993) |
| Spherical disproportion | 0.832 (0.005–0.962) | RLN | 0.999 (0.498–1.000) |
| Sphericity | 0.893 (0.008–0.977) | RP | 0.851 (0.006–0.967) |
| Maximum 3D diameter | 0.528 (0.001–0.852) | LGLRE | 0.991 (0.095–0.998) |
| Volume cc | 0.900 (0.009–0.979) | HGLRE | 0.948 (0.018–0.989) |
| Extruded surface area | 0.984 (0.056–0.997) | SRLGLE | 0.829 (0.005–0.962) |
| Extruded volume | 0.968 (0.029–0.994) | SRHGLE | 0.832 (0.005–0.962) |
| Extruded surface: volume ratio | 0.720 (0.000–0.287) | Box-counting dimension | 0.795 (0.004–0.952) |
| LRLGLE | 0.982 (0.050–0.996) | LRHGLE | 0.714 (0.002–0.928) |
| Correlation dimension | 0.901 (0.009–0.979) | LRE | 0.795 (0.004–0.952) |
| SRE | 0.714 (0.002–0.928) | GLN | 0.933 (0.014–0.986) |