Table 2.
Clinical manifestations of Behcet disease according to onset of age
| Clinical feature | Total (n = 188) | ≤ 40 Years (n = 144) | > 40 Years (n = 44) | p value |
|---|---|---|---|---|
| Age, yr | 44.6 ± 10.9 | 40.9 ± 9.0 | 56.7 ± 7.4 | < 0.00 |
| Onset age, yr | 32.2 ± 11.1 | 27.7 ± 7.8 | 47.2 ± 6.0 | < 0.00 |
| Disease duration, yr | 14.2 ± 9.3 | 14.9 ± 9.6 | 11.8 ± 7.9 | NS |
| Follow-up duration, yr | 4.7 ± 3.7 | 4.3 ± 3.6 | 5.9 ± 3.9 | 0.01 |
| Positive HLA-B51 (performed in 96 patients) | 39 (40.6) | 32 (45.1) | 7 (28.0) | NS |
| Positive pathergy test (performed in 103 patients) | 30 (29.1) | 23 (28.0) | 7 (33.3) | NS |
| Oral ulcer | 186 (98.9) | 143 (99.3) | 43 (97.7) | NS |
| Genital ulcer | 160 (85.1) | 125 (86.8) | 35 (79.5) | NS |
| Skin lesion | 151 (80.3) | 117 (81.3) | 34 (77.3) | NS |
| Pseudofolliculitis | 85 (45.2) | 67 (46.5) | 18 (40.9) | NS |
| Erythema nodosum | 99 (52.7) | 78 (54.2) | 21 (47.7) | NS |
| Joint involvements | 120 (63.8) | 93 (64.6) | 27 (61.4) | NS |
| Arm | 69 (36.7) | 56 (38.9) | 13 (29.5) | NS |
| Leg | 88 (46.8) | 69 (47.9) | 19 (43.2) | NS |
| Shoulder | 21 (11.2) | 18 (12.5) | 3 (6.8) | NS |
| Hip | 6 (3.2) | 3 (2.1) | 3 (6.8) | NS |
| Inflammatory back pain | 64 (34.0) | 49 (34.0) | 15 (34.1) | NS |
| Major organ involvement | 75 (39.9) | 55 (38.2) | 20 (45.5) | NS |
| Uveitis | 52 (27.7) | 40 (27.8) | 12 (27.3) | NS |
| Neurologic | 11 (11.2) | 6 (4.2) | 7 (15.9) | 0.007 |
| Gastrointestinal | 21 (11.2) | 14 (9.7) | 7 (15.9) | NS |
| Vascular | 8 (4.3) | 5 (3.5) | 3 (6.8) | NS |
Values are presented as mean ± SD or number (%).
NS, not significant; HLA, human leukocyte antigen.