Table 2.
Comparison of clinical variables according to the result of sputum AFB culture conversion at 2 months
| Variable | Conversion, yes (n = 69) | Conversion, no (n = 36) | p value |
|---|---|---|---|
| Age, yr | 61.14 ± 13.58 | 56.47 ± 16.85 | 0.13 |
| Male sex | 50 (72.5) | 32 (88.9) | 0.05 |
| Glucose mg/dL | 186.39 ± 101.77 | 226.97 ± 131.18 | 0.08 |
| HbA1c % | 8.04 ± 2.08 | 8.17 ± 1.89 | 0.82 |
| Lab | |||
| Hemoglobin | 12.37 (1.87) | 12.94 (1.68) | 0.13 |
| Albumin | 3.66 (0.66) | 3.60 (0.49) | 0.63 |
| GFR | 85.85 (39.38) | 95.17 (33.55) | 0.23 |
| CRP | 4.67 (4.60) | 8.68 (16.38) | 0.22 |
| AST | 35.54 (47.48) | 33.39 (43.87) | 0.83 |
| ALT | 29.74 (35.08) | 31.72 (63.77) | 0.84 |
| Comorbidity | |||
| LC | 7 (10.1) | 6 (16.7) | 0.34 |
| Chronic lung disease | 6 (8.7) | 4 (11.1) | 0.69 |
| Cancer | 10 (14.5) | 1 (2.8) | 0.06 |
| CKD | 12 (17.4) | 3 (8.3) | 0.21 |
| Immunosuppressed | 14 (20.3) | 6 (16.7) | 0.65 |
| Autoimmune | 2 (2.9) | 0 | 0.30 |
| Previous TB his- tory | 13 (18.8) | 8 (22.2) | 0.68 |
| Statin | 22 (31.9) | 9 (25.0) | 0.46 |
| Metformin | 42 (60.9) | 20 (55.6) | 0.60 |
| Insulin | 22 (31.9) | 7 (19.4) | 0.18 |
| Cavity | 24 (34.8) | 15 (41.7) | 0.49 |
| Drug resistance | 7 (10.1) | 13 (36.1) | < 0.01 |
| AFB smear grade | |||
| 0 | 41 (59.4) | 15 (41.7) | 0.08 |
| 1 | 8 (11.6) | 4 (11.1) | 0.94 |
| 2 | 3 (4.3) | 5 (13.9) | 0.08 |
| 3 | 8 (11.6) | 5 (13.9) | 0.74 |
| 4 | 9 (13.0) | 7 (19.4) | 0.39 |
| Recurrence with-in 1 year | 7 (10.1) | 2 (5.6) | 0.43 |
Values are presented as mean ± SD or number (%).
AFB, acid-fast bacilli; HbA1c, glycosylated hemoglobin; GFR, glomerular filtration rate; CRP, C-reactive protein; AST, aspartate transaminase; ALT, alanine transaminase; LC, liver cirrhosis; CKD, chronic kidney disease; TB, tuberculosis.