Table 2. Atheroma burden and remodelling parameters by absence and presence of obstructive CAD.
| Characteristic | Non-obstructive CAD (n=87) | Obstructive CAD (n=87) | P value | Adjusted P value* |
|---|---|---|---|---|
| Percent atheroma volume (%) | 25.4±9.1 | 36.1±9.8 | <0.0001 | 0.0008 |
| Total atheroma volume (mm3) | 98.8±46.9 | 140.8±58.7 | <0.0001 | 0.110 |
| Percent images containing plaque (%) | 35.7±32.6 | 70.0±30.5 | <0.0001 | 0.0008 |
| EEM volume (mm3) | 388.6±113.7 | 392.7±128.1 | 0.910 | 0.400 |
| Lumen volume (mm3) | 289.7±91.8 | 251.9±92.8 | 0.005 | 0.050 |
| Remodelling index | 0.96±0.25 | 0.96±0.20 | 0.89 | – |
| Constrictive remodelling (%) | 40.2 | 46.4 | 0.41 | – |
| Expansive remodelling (%) | 25.3 | 25.0 | 0.97 | – |
Measures of arterial wall remodelling throughout the segment of vessel evaluated and at the site containing the greatest plaque area in age and ethnicity matched females without and with obstructive CAD. Univariate results expressed as mean ± SD. Multivariate results expressed as least square mean ± SEM. *, adjusted for differences in clinical characteristics (congestive heart failure, hypertension, metabolic syndrome, previous myocardial infarction, LDL cholesterol, triglyceride and diastolic blood pressure). CAD, coronary artery disease; LDL, low-density lipoprotein; EEM, external elastic membrane; SEM, standard error of the mean; SD, standard deviation.