Table1. Baseline characteristics of the study population.
Variables | Total, n=150 | Non-dialysis, n=90 | Hemodialysis, n=60 | P |
---|---|---|---|---|
Age (years) | 52±15 | 55±15 | 48±15 | 0.009 |
Male gender | 85 (56.7) | 53 (58.9) | 32 (53.3) | 0.6 |
BMI (kg/m2) | 26.2±4.7 | 27.0±4.8 | 25.0±4.3 | 0.009 |
Overweight/obesity | 80 (53.3) | 56 (62.2) | 24 (40.0) | 0.012 |
Abdominal obesity | 51 (34.0) | 35 (38.9) | 16 (26.7) | 0.17 |
Current smoking | 2 (1.3) | 1 (1.1) | 1 (1.7) | 0.8 |
Current alcohol use | 24 (16.0) | 19 (21.1) | 5 (8.3) | 0.07 |
Hypertension | 131 (87.3) | 77 (85.6) | 54 (90.0) | 0.3 |
Hypertension medication | 118 (78.7) | 70 (77.8) | 48 (80.0) | 0.9 |
Diabetes | 49 (32.7) | 32 (35.6) | 17 (28.3) | 0.5 |
Current dyslipidemia | 93 (62.0) | 55 (61.1) | 38 (63.3) | 0.9 |
Previous CVE | 27 (18.0) | 17 (18.9) | 10 (16.7) | 0.8 |
Blood glucose (g/L) | 1.18±0.58 | 1.16±0.44 | 1.27±0.70 | 0.289 |
Hemoglobin (g/dL) | 9.1±2.4 | 10.3±2.2 | 8.4±1.9 | <0.0001 |
Serum calcium (mg/L) | 8.8±1.6 | 8.79±0.88 | 8.84±1.96 | 0.858 |
Serum phosphate (mg/L) | 4.2±1.7 | 4.27±1.58 | 4.09±1.66 | 0.529 |
Ca-Ph product (mg2/dL2) | 37.3±15.8 | 37.16±12.88 | 37.59±16.11 | 0.8 |
Total cholesterol (g/L) | 1.78±0.95 | 1.94±1.07 | 1.56±0.35 | 0.013 |
HDL cholesterol (g/L) | 0.45±0.21 | 0.52±0.22 | 0.38±0.20 | 0.0002 |
Triglycerides (g/L) | 1.05±0.49 | 1.19±1.00 | 0.88±0.33 | 0.032 |
LDL cholesterol (g/L) | 1.08±0.89 | 1.13±0.65 | 1.09±0.55 | 0.6 |
Median GFR (mL/min/1.73 m2) | 26.5 | 27.0 | 0.29 | 0.048 |
Peripheral | ||||
SBP (mmHg) | 143±25 | 144±25 | 148±24 | 0.771 |
DBP (mmHg) | 91±16 | 89±16 | 93±17 | 0.216 |
PP (mmHg) | 53±16 | 55±16 | 56±14 | 0.386 |
HR (bpm) | 80±13 | 78±12 | 78±12 | 0.881 |
Central | ||||
SBP (mmHg) | 130±22 | 131±22 | 134±21 | 0.469 |
DBP (mmHg) | 92±17 | 91±17 | 94±18 | 0.15 |
PP (mmHg) | 38±14 | 40±14 | 39±11 | 0.434 |
MAP (mmHg) | 104±18 | 104±18 | 108±18 | 0.218 |
MobPWV (m/s) | 8.2±1.8 | 8.5±2.0 | 7.9±1.4 | 0.025 |
Estimated cfPWV (m/s) | 10.0±2.0 | 10.3±2.2 | 9.6±1.6 | 0.025 |
MobPWV* (m/s) | 8.2±1.6 | 8.4±1.7 | 7.9±1.4 | 0.042 |
Estimated cfPWV* (m/s) | 10.0±1.8 | 10.3±1.9 | 9.7±1.6 | 0.042 |
Data are mean ± standard deviation or number (percentages); PWV*, pulse wave velocity adjusted for age, MAP, sex, body mass index. HDL, high-density lipoprotein; LDL, non-high-density lipoprotein; Ca-Ph, calcium-phosphate; CVE, cardiovascular event.