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. 2018 Aug;10(8):5039–5046. doi: 10.21037/jtd.2018.07.48

Table 4. Cox proportional model for staging groupings.

Factors AJCC 7th staging AJCC 8th staging Japanese 11th classification
HR (95% CI) P HR (95% CI) P HR (95% CI) P
Stage grouping
   0 Reference Reference Reference
   I 2.886 (0.581–14.327) 0.195
   II 2.855 (1.220–6.683) 0.016 2.452 (0.996–6.037) 0.051 5.646 (1.281–24.879) 0.022
   III 7.195 (3.161–16.378) <0.001 5.618 (2.450–12.881) <0.001 21.178 (4.829–92.883) <0.001
   IV 12.019 (3.645–39.633) <0.001
Concordance index 0.813 (0.732–0.896) 0.805 (0.726–0.885) 0.837 (0.766–0.908)

AJCC, the American Joint Committee on Cancer; HR, hazard ratio; CI, confidence interval.