Predicting value for mortality in patients with ILD assessed by Cox regression model. Using Cox regression analysis, KL-6 was the best independent predictor of mortality after adjustment for other covariates (HR, 1.90; 95% CI, 1.29–2.79; P=0.001). Only FVC% is the predictor of mortality in multivariate analysis (n=322). FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; DLCO, diffusion capacity for carbon monoxide; TLC, total lung capacity; GGO, ground glass opacity; HC, honeycombing; KL-6, Klebs von den Lungen-6; CI, confidence interval; ILD, interstitial lung disease.