Table 3. Compared main indicators in male subgroup.
| Research indicators | Male subgroup | ||||
|---|---|---|---|---|---|
| Underweight BMI <18.5 (n=47) |
Normal weight 18.5≤ BMI <25 (n=276) |
Overweight 25≤ BMI <30 (n=163) |
Obesity BMI ≥30 (n=87) | P value | |
| Main indicators of lung function | |||||
| FEV1 | 46.10 (29.80–63.90) | 44.30 (32.43–62.98) | 50.30 (34.50–69.80) | 68.60 (52.80-78.30) | <0.001 |
| FVC* | 72.98 (35.10–104.90) | 66.26 (24.30–125.80) | 66.72 (33.00–98.80) | 76.89 (36.10-113.40) | <0.001 |
| PEF | 34.30 (27.10–57.80) | 40.15 (27.03–56.30) | 49.90 (32.90–69.80) | 65.40 (51.90-79.40) | <0.001 |
| FEF25 | 18.60 (8.70–33.30) | 18.15 (10.90–34.25) | 26.80 (13.10–47.40) | 29.70 (23.15-43.35) | <0.001 |
| FEF50 | 14.45 (8.73–32.58) | 15.30 (9.60–26.58) | 20.30 (11.00–38.70) | 33.70 (22.80-51.20) | <0.001 |
| FEF75 | 24.30 (16.43–49.08) | 22.85 (14.90–38.20) | 25.10 (14.90–44.20) | 44.45 (28.75-65.30) | <0.001 |
| TLC | 77.85 (66.28–93.63) | 77.10 (64.05–87.40) | 73.45 (63.20–86.60) | 79.90 (69.10-86.90) | 0.136 |
| RV | 99.10 (77.63–141.13) | 101.50 (80.48–128.65) | 101.60 (74.43–127.38) | 103.00 (83.30–118.90) | 0.671 |
| DLCO* | 40.79 (8.09–79.30) | 45.61 (3.80–188.20) | 53.36 (4.33–108.40) | 72.20 (27.60–117.30) | <0.001 |
| DLCO/VA* | 47.52 (5.70–116.70) | 56.32 (1.29–185.50) | 71.61 (1.69–186.30) | 97.03 (43.90–171.80) | <0.001 |
| PAP (by Doppler cardiac ultrasound) | 34.00 (31.00-44.00) | 34.00 (28.00–41.75) | 34.50 (28.00–41.25) | 32.00 (28.50–34.00) | 0.252 |
| Times of AECOPD in years | 6.00 (2.50–8.75) | 2.00 (1.00–4.00) | 2.00 (1.00–5.75) | 2.00 (1.00–5.75) | 0.110 |
| Moderate exacerbations in 3 years | 1.00 (0.00–4.25) | 0.00 (0.00–2.00) | 0.00 (0.00–2.75) | 1.00 (0.00–5.50) | 0.257 |
| Severe exacerbations in3 years | 2.50 (1.00–5.25) | 1.00 (1.00–2.00) | 1.00 (1.00–1.75) | 0.50 (0.00–1.00) | 0.003 |
| Frequency of AECOPD per year | 2.00 (0.83–2.95) | 0.70 (0.30–1.30) | 0.70 (0.30–1.93) | 0.70 (0.31–1.93) | 0.080 |
Data presented as median (IQR) unless specified. *, data presented as mean (range). BMI, body mass index; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; PEF, peak expiratory flow; FEF, forced expiratory flow; TLC, total lung capacity; RV, residual volume; DLCO, diffusing capacity of carbon monoxide; DLCO/VA, ratio of carbon monoxide diffusion capacity to alveolar ventilation; PAP, pulmonary arterial pressure; AECOPD, acute exacerbation of chronic obstructive pulmonary disease.