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. 2018 Sep 10;7(9):713–719. doi: 10.1002/open.201800177

Figure 3.

Figure 3

Comparison of gefitinib binding at the GAK ATP binding site. Gefitinib binding at the ATP binding site of a) GAK_1 and b) GAK_2. Gefitinib is shown as a stick model with the backbone carbons in green (GAK_1) and cyan (GAK_2) and the 2 F oF c electron density map (1σ). c) Superimposed structures of GAK_2 (green ribbon structure) and EGFR (orange ribbon structure). Gefitinib molecules are shown as a green (GAK_2) and orange (EGFR) stick model.