Table 19.
One-, Two-, Five-, and Ten-Year Relative Survival Ratesa,b with 95% Confidence Intervals for Brain and Other Central Nervous System Tumors by Behavior and Sitec, SEER 18 Registries, 2000-2015 (varying)d
| ICD-O-3 Site Code | Site c | Malignant (2000-2014) | Non-Malignant (2004-2015) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-Year | 5-Year | 10-Year | 1-Year | 5-Year | 10-Year | ||||||||||
| N e | % | 95% CI | % | 95% CI | % | 95% CI | N e | % | 95% CI | % | 95% CI | % | 95% CI | ||
| C71.0 | Cerebrum | 3,938 | 52.1 | 50.4-53.7 | 28.6 | 27.1-30.2 | 24.2 | 22.5-25.8 | 625 | 85.7 | 82.5-88.4 | 80.4 | 76.4-83.9 | 78.4 | 72.8-82.9 |
| C71.1 | Frontal lobe of the brain | 19,445 | 61.4 | 60.7-62.1 | 34.2 | 33.4-34.9 | 25.6 | 24.8-26.4 | 1,818 | 87.0 | 85.2-88.6 | 81.3 | 78.8-83.5 | 76.6 | 72.6-80.1 |
| C71.2 | Temporal lobe of the brain | 13,933 | 58.2 | 57.3-59.0 | 23.1 | 22.3-23.9 | 17.4 | 16.6-18.2 | 1,634 | 93.2 | 91.7-94.4 | 90.3 | 88.3-92.0 | 87.8 | 84.8-90.2 |
| C71.3 | Parietal lobe of the brain | 8,891 | 51.4 | 50.3-52.5 | 20.2 | 19.2-21.1 | 15.1 | 14.1-16.1 | 814 | 84.7 | 81.8-87.1 | 79.2 | 75.5-82.5 | 76.2 | 71.0-80.7 |
| C71.4 | Occipital lobe of the brain | 2,244 | 53.4 | 51.3-55.6 | 21.4 | 19.5-23.3 | 17.5 | 15.6-19.4 | 335 | 91.6 | 87.6-94.3 | 88.1 | 82.8-91.8 | 83.4 | 74.1-89.5 |
| C71.5 | Ventricle | 1,480 | 75.8 | 73.4-77.9 | 62.6 | 59.8-65.2 | 58.4 | 55.3-61.3 | 1,497 | 93.3 | 91.8-94.6 | 89.8 | 87.6-91.5 | 84.6 | 80.8-87.8 |
| C71.6 | Cerebellum | 4,518 | 85.1 | 84.0-86.2 | 71.5 | 70.0-73.0 | 67.0 | 65.3-68.6 | 2,179 | 93.1 | 91.8-94.2 | 89.5 | 87.6-91.1 | 86.0 | 82.8-88.6 |
| C71.7 | Brain stem | 3,701 | 70.9 | 69.4-72.4 | 50.0 | 48.2-51.7 | 45.3 | 43.3-47.2 | 885 | 90.5 | 88.1-92.4 | 86.0 | 82.8-88.7 | 80.8 | 75.2-85.2 |
| C71.8-C71.9 | Other brain | 17,413 | 44.7 | 43.9-45.5 | 22.8 | 22.1-23.5 | 18.5 | 17.8-19.2 | 3,200 | 79.5 | 77.9-81.0 | 73.1 | 71.2-75.0 | 67.8 | 64.9-70.5 |
| C72.0-C72.1 | Spinal cord and cauda equina | 2,774 | 89.8 | 88.5-90.9 | 81.5 | 79.7-83.1 | 76.9 | 74.6-79.0 | 4,622 | 98.8 | 98.3-99.2 | 98.2 | 97.2-98.9 | 97.3 | 94.6-98.7 |
| C72.2-C72.5 | Cranial nerves | 1,000 | 96.9 | 95.5-97.8 | 93.7 | 91.7-95.2 | 92.2 | 89.6-94.1 | 16,792 | 99.5 | 99.3-99.7 | 99.5 | 99.3-99.7 | 99.5 | 99.3-99.7 |
| C72.8-C72.9 | Other nervous system | 731 | 62.9 | 59.1-66.4 | 46.5 | 42.3-50.6 | 44.0 | 39.2-48.7 | 436 | 97.4 | 94.9-98.7 | 93.2 | 88.5-96.0 | 84.3 | 74.0-90.8 |
| C70.0-C70.9 | Meninges (cerebral and spinal) | 1,409 | 81.9 | 79.7-84.0 | 64.3 | 61.1-67.2 | 57.2 | 53.3-60.8 | 84,459 | 92.6 | 92.4-92.8 | 86.8 | 86.4-87.2 | 81.5 | 80.8-82.2 |
| C75.1-C75.2 | Pituitary and craniopharyngeal duct | 327 | 86.8 | 82.3-90.2 | 75.0 | 68.8-80.1 | 70.9 | 63.6-77.0 | 43,739 | 97.8 | 97.6-97.9 | 96.0 | 95.6-96.3 | 93.8 | 93.0-94.4 |
| C75.3 | Pineal | 876 | 88.6 | 86.2-90.6 | 77.2 | 74.0-80.1 | 72.6 | 68.7-76.1 | 405 | 91.9 | 88.5-94.3 | 86.2 | 81.2-89.9 | 81.3 | 73.7-86.9 |
| C30.0g | Olfactory tumors of the nasal cavity | 480 | 91.4 | 88.2-93.7 | 79.4 | 74.5-83.4 | 65.7 | 58.6-71.9 | -- | -- | -- | -- | -- | -- | -- |
| All Codes | All Sites | 83,160 | 59.9 | 59.6-60.3 | 35.0 | 34.6-35.3 | 29.3 | 28.9-29.7 | 163,440 | 94.5 | 94.4-94.7 | 90.7 | 90.5-91.0 | 87.2 | 86.8-87.7 |
aThe cohort analysis of survival rates was utilized for calculating the survival estimates presented in this table. Long-term cohort-based survival estimates reflect the survival experience of individuals diagnosed over the time period, and they may not necessarily reflect the long-term survival outlook of newly diagnosed cases.
bRates are an estimate of the percentage of patients alive at one, two, five, and ten years, respectively. Rates were not presented for categories with 50 or fewer cases and were suppressed for rates where fewer than 16 cases were surviving within a category.
cThe sites referred to in this table are loosely based on the categories and site codes defined in the SEER Site/Histology Validation List.
dEstimated by CBTRUS using Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2017 Sub (2000-2015) <Katrina/Rita Population Adjustment> - Linked To County Attributes - Total U.S., 1969-2016 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 2018, based on the November 2017 submission.
eTotal number of case that occurred within the SEER registries between 2000 and 2015.
fICD-O-3 histology codes 9522-9523 only.
-- Counts and rates are not presented for categories with 50 or fewer cases and were suppressed for rates where fewer than 16 cases were surviving within a category. The suppressed cases are included in the counts and rates for totals.
Abbreviation: CBTRUS, Central Brain Tumor Registry of the United States; SEER, Survival, Epidemiology, and End Results; CI, confidence interval