Table 21.
One-, Two-, Five-, and Ten-Year Relative Survival Ratesa,b with 95% Confidence Intervals for Selected Malignant Brain and Other Central Nervous System Tumors by Age Group, SEER 18 Registries, 2000-2015c
| Histology | Age Group (years) | N d | 1-Year | 2-Year | 5-Year | 10-Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | |||
| Pilocytic astrocytoma | 0-19 | 3,039 | 98.7 | 98.2-99.1 | 98.2 | 97.6-98.6 | 96.6 | 95.8-97.2 | 95.7 | 94.7-96.5 |
| 20-44 | 826 | 96.7 | 95.2-97.8 | 94.5 | 92.6-95.9 | 91.5 | 89.1-93.4 | 86.1 | 82.7-88.9 | |
| 45-54 | 154 | 94.4 | 89.0-97.2 | 86.1 | 79.1-90.9 | 78.8 | 70.3-85.1 | 76.0 | 65.8-83.5 | |
| 55-64 | 95 | 95.2 | 87.2-98.3 | 89.9 | 80.4-95.0 | 83.0 | 72.1-89.9 | 78.7 | 64.5-87.7 | |
| 65-74 | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
| 75+ | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
| Diffuse astrocytoma | 0-19 | 977 | 93.1 | 91.2-94.5 | 87.6 | 85.3-89.6 | 83.5 | 80.8-85.8 | 81.2 | 78.2-83.8 |
| 20-44 | 2,330 | 93.5 | 92.4-94.5 | 87.4 | 85.9-88.8 | 69.2 | 67.1-71.2 | 49.6 | 46.9-52.2 | |
| 45-54 | 1,039 | 77.4 | 74.7-79.9 | 63.0 | 59.8-65.9 | 44.9 | 41.5-48.2 | 32.8 | 29.1-36.5 | |
| 55-64 | 909 | 58.0 | 54.6-61.2 | 38.3 | 35.0-41.6 | 23.0 | 20.0-26.2 | 14.6 | 11.5-18.1 | |
| 65-74 | 681 | 43.2 | 39.4-47.0 | 26.5 | 23.0-30.1 | 15.4 | 12.4-18.7 | 11.6 | 8.3-15.6 | |
| 75+ | 557 | 25.1 | 21.4-28.9 | 13.0 | 10.1-16.2 | 6.4 | 4.1-9.5 | 1.2 | 0.1-5.1 | |
| Anaplastic astrocytoma | 0-19 | 341 | 68.9 | 63.6-73.6 | 39.3 | 33.8-44.6 | 27.0 | 22.0-32.2 | 19.5 | 14.6-24.9 |
| 20-44 | 1,535 | 89.5 | 87.8-90.9 | 75.9 | 73.5-78.1 | 55.2 | 52.2-58.0 | 39.3 | 35.9-42.6 | |
| 45-54 | 789 | 74.7 | 71.4-77.7 | 51.7 | 47.9-55.3 | 31.5 | 27.8-35.3 | 22.9 | 19.0-27.0 | |
| 55-64 | 810 | 55.4 | 51.7-58.8 | 30.8 | 27.4-34.2 | 13.3 | 10.6-16.2 | 6.1 | 3.8-9.2 | |
| 65-74 | 628 | 37.1 | 33.2-41.0 | 18.0 | 14.9-21.4 | 7.9 | 5.6-10.8 | 5.0 | 3.0-7.9 | |
| 75+ | 433 | 18.0 | 14.4-22.0 | 8.8 | 6.1-12.1 | 1.1 | 0.3-3.2 | 0.6 | 0.1-2.8 | |
| Glioblastoma | 0-19 | 516 | 59.1 | 54.7-63.3 | 33.4 | 29.2-37.7 | 16.6 | 13.2-20.4 | 12.1 | 8.8-15.9 |
| 20-44 | 3,253 | 70.4 | 68.8-72.0 | 41.6 | 39.8-43.3 | 19.1 | 17.6-20.7 | 10.9 | 9.6-12.4 | |
| 45-54 | 6,360 | 57.9 | 56.7-59.2 | 25.9 | 24.7-27.0 | 7.7 | 7.0-8.5 | 3.8 | 3.2-4.6 | |
| 55-64 | 10,027 | 46.6 | 45.6-47.6 | 18.3 | 17.5-19.1 | 4.7 | 4.2-5.2 | 1.8 | 1.4-2.3 | |
| 65-74 | 9,093 | 30.0 | 29.0-31.0 | 11.1 | 10.4-11.8 | 2.6 | 2.2-3.0 | 1.0 | 0.7-1.5 | |
| 75+ | 7,367 | 12.7 | 12.0-13.6 | 3.8 | 3.3-4.4 | 1.0 | 0.7-1.3 | 0.3 | 0.1-0.8 | |
| Oligodendroglioma | 0-19 | 240 | 96.6 | 93.3-98.3 | 94.8 | 90.9-97.0 | 90.9 | 86.0-94.1 | 88.6 | 83.1-92.3 |
| 20-44 | 1,720 | 98.7 | 98.0-99.2 | 96.5 | 95.5-97.4 | 88.3 | 86.4-89.9 | 71.8 | 68.9-74.5 | |
| 45-54 | 778 | 94.8 | 92.8-96.2 | 90.3 | 87.8-92.3 | 81.0 | 77.6-83.9 | 64.5 | 59.7-68.9 | |
| 55-64 | 427 | 89.3 | 85.8-92.0 | 80.0 | 75.5-83.7 | 69.7 | 64.2-74.5 | 53.3 | 45.9-60.2 | |
| 65-74 | 181 | 81.2 | 74.2-86.5 | 73.0 | 64.9-79.4 | 54.4 | 45.0-62.8 | 38.1 | 27.0-49.1 | |
| 75+ | 96 | 63.0 | 51.3-72.5 | 51.0 | 38.9-61.9 | 39.1 | 25.9-52.1 | -- | -- | |
| Anaplastic oligodendroglioma | 0-19 | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| 20-44 | 575 | 94.6 | 92.3-96.2 | 85.5 | 82.1-88.3 | 72.1 | 67.8-75.9 | 56.3 | 51.0-61.4 | |
| 45-54 | 385 | 89.7 | 86.0-92.4 | 78.8 | 74.0-82.8 | 63.7 | 57.8-68.9 | 46.9 | 40.0-53.5 | |
| 55-64 | 311 | 78.3 | 73.0-82.6 | 63.4 | 57.3-68.8 | 46.1 | 39.6-52.3 | 33.5 | 26.3-40.8 | |
| 65-74 | 139 | 57.1 | 48.1-65.1 | 38.4 | 29.7-47.0 | 22.1 | 14.3-31.0 | 16.1 | 8.4-26.1 | |
| 75+ | 57 | 40.5 | 26.8-53.7 | -- | -- | -- | -- | -- | -- | |
| Ependymal tumors | 0-19 | 880 | 95.3 | 93.6-96.5 | 88.5 | 86.1-90.6 | 77.0 | 73.6-79.9 | 68.4 | 64.4-72.0 |
| 20-44 | 987 | 97.4 | 96.1-98.2 | 95.5 | 93.9-96.7 | 91.8 | 89.6-93.6 | 88.3 | 85.3-90.7 | |
| 45-54 | 570 | 95.8 | 93.6-97.2 | 93.2 | 90.5-95.1 | 89.5 | 86.1-92.1 | 87.3 | 83.0-90.6 | |
| 55-64 | 413 | 92.2 | 89.0-94.6 | 89.2 | 85.3-92.1 | 86.7 | 81.9-90.2 | 84.6 | 77.7-89.5 | |
| 65-74 | 208 | 88.5 | 82.6-92.5 | 82.7 | 75.7-87.8 | 81.2 | 73.6-86.8 | 67.3 | 52.9-78.2 | |
| 75+ | 97 | 68.1 | 56.7-77.1 | 63.4 | 51.0-73.5 | 51.2 | 36.4-64.3 | 30.7 | 13.7-49.6 | |
| Oligoastrocytic tumors | 0-19 | 126 | 93.6 | 87.5-96.8 | 88.5 | 81.2-93.1 | 81.2 | 72.6-87.3 | 76.5 | 67.0-83.6 |
| 20-44 | 1,194 | 96.9 | 95.6-97.7 | 91.0 | 89.1-92.6 | 73.8 | 70.8-76.5 | 55.3 | 51.4-58.9 | |
| 45-54 | 450 | 89.8 | 86.5-92.3 | 79.4 | 75.1-83.0 | 66.6 | 61.5-71.2 | 48.2 | 41.5-54.5 | |
| 55-64 | 259 | 74.0 | 68.0-79.0 | 51.6 | 45.0-57.8 | 34.2 | 27.7-40.8 | 26.4 | 19.3-34.0 | |
| 65-74 | 145 | 66.3 | 57.7-73.6 | 48.4 | 39.5-56.7 | 26.6 | 18.5-35.4 | 13.3 | 6.2-23.2 | |
| 75+ | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
| Glioma malignant, NOS | 0-19 | 1,969 | 78.6 | 76.6-80.4 | 68.0 | 65.8-70.1 | 65.1 | 62.8-67.3 | 63.4 | 61.0-65.7 |
| 20-44 | 1,058 | 88.2 | 86.0-90.0 | 80.0 | 77.3-82.4 | 69.1 | 65.9-72.2 | 56.6 | 52.4-60.6 | |
| 45-54 | 509 | 75.0 | 70.9-78.6 | 60.3 | 55.7-64.6 | 49.7 | 44.9-54.4 | 39.5 | 34.0-44.9 | |
| 55-64 | 452 | 58.9 | 54.1-63.5 | 45.3 | 40.3-50.2 | 35.7 | 30.6-40.9 | 29.4 | 23.5-35.4 | |
| 65-74 | 430 | 39.9 | 35.2-44.7 | 26.5 | 22.1-31.1 | 17.7 | 13.6-22.3 | 15.6 | 11.1-20.8 | |
| 75+ | 787 | 18.9 | 16.1-21.9 | 14.1 | 11.5-17.0 | 9.7 | 7.0-12.7 | 8.5 | 5.5-12.4 | |
| Neuronal and mixed neuronal-glial tumors | 0-19 | 73 | 94.4 | 85.8-97.9 | 88.5 | 78.2-94.1 | 83.6 | 72.1-90.6 | 83.6 | 72.1-90.6 |
| 20-44 | 161 | 95.6 | 90.7-97.9 | 90.1 | 83.9-94.0 | 78.5 | 70.3-84.7 | 63.9 | 53.1-72.8 | |
| 45-54 | 143 | 93.8 | 88.0-96.9 | 90.3 | 83.5-94.4 | 85.1 | 77.0-90.5 | 77.3 | 64.8-85.8 | |
| 55-64 | 124 | 91.4 | 84.3-95.4 | 82.5 | 73.5-88.7 | 69.7 | 58.5-78.5 | 51.3 | 36.4-64.4 | |
| 65-74 | 68 | 86.2 | 74.2-92.9 | 84.5 | 71.2-92.0 | 76.1 | 58.3-87.1 | 55.1 | 28.1-75.6 | |
| 75+ | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
| Embryonal tumors | 0-19 | 2,312 | 81.5 | 79.8-83.1 | 71.8 | 69.9-73.7 | 62.8 | 60.6-64.8 | 56.7 | 54.3-59.0 |
| 20-44 | 627 | 87.1 | 84.1-89.5 | 80.0 | 76.5-83.1 | 66.9 | 62.6-70.8 | 58.9 | 54.1-63.4 | |
| 45-54 | 91 | 82.4 | 72.7-88.9 | 69.8 | 58.9-78.4 | 54.0 | 42.2-64.5 | 38.4 | 25.7-50.9 | |
| 55-64 | 52 | 68.2 | 53.1-79.3 | 48.7 | 33.8-62.1 | -- | -- | -- | -- | |
| 65-74 | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
| 75+ | -- | -- | -- | -- | -- | -- | -- | -- | -- | |
| Meningioma | 0-19 | -- | -- | -- | 81.4 | 52.4-93.7 | 81.4 | 52.4-93.7 | 81.4 | 52.4-93.7 |
| 20-44 | 149 | 94.7 | 89.4-97.4 | 94.1 | 88.6-97.0 | 87.7 | 80.5-92.3 | 78.7 | 69.7-85.3 | |
| 45-54 | 195 | 93.1 | 88.2-96.0 | 85.8 | 79.7-90.2 | 77.9 | 70.6-83.6 | 70.8 | 62.2-77.8 | |
| 55-64 | 291 | 88.2 | 83.6-91.5 | 81.1 | 75.7-85.4 | 68.7 | 62.1-74.4 | 59.9 | 52.2-66.7 | |
| 65-74 | 270 | 80.6 | 75.0-85.1 | 69.5 | 63.0-75.2 | 51.4 | 43.8-58.5 | 46.1 | 36.6-55.1 | |
| 75+ | 307 | 63.4 | 57.1-69.0 | 55.6 | 48.7-61.9 | 46.4 | 38.1-54.2 | 34.3 | 24.1-44.7 | |
| Lymphoma | 0-19 | 70 | 84.0 | 72.9-90.8 | 76.5 | 64.4-84.9 | 71.7 | 59.2-81.0 | 67.3 | 53.9-77.7 |
| 20-44 | 834 | 57.7 | 54.2-61.0 | 52.0 | 48.4-55.4 | 45.9 | 42.2-49.5 | 40.7 | 36.8-44.6 | |
| 45-54 | 784 | 63.0 | 59.5-66.4 | 54.2 | 50.5-57.7 | 42.7 | 38.8-46.5 | 32.2 | 28.1-36.4 | |
| 55-64 | 1,121 | 62.5 | 59.5-65.3 | 53.6 | 50.5-56.6 | 39.8 | 36.5-43.1 | 29.3 | 25.6-33.1 | |
| 65-74 | 1,311 | 51.5 | 48.7-54.3 | 42.6 | 39.7-45.5 | 29.0 | 26.0-32.1 | 18.9 | 15.5-22.7 | |
| 75+ | 1,083 | 34.0 | 31.0-37.0 | 24.6 | 21.8-27.5 | 16.1 | 13.2-19.2 | 11.6 | 7.9-16.1 | |
| TOTAL | 0-19 | 11,985 | 87.4 | 86.8-88.0 | 80.0 | 79.3-80.8 | 74.1 | 73.2-74.9 | 70.7 | 69.7-71.6 |
| 20-44 | 16,324 | 86.8 | 86.3-87.4 | 76.3 | 75.6-77.0 | 62.2 | 61.4-63.1 | 50.1 | 49.1-51.1 | |
| 45-54 | 12,738 | 69.8 | 68.9-70.6 | 48.5 | 47.6-49.4 | 33.5 | 32.6-34.4 | 26.2 | 25.2-27.2 | |
| 55-64 | 15,805 | 54.4 | 53.6-55.2 | 31.6 | 30.8-32.4 | 18.5 | 17.8-19.2 | 13.7 | 13.0-14.4 | |
| 65-74 | 13,797 | 37.3 | 36.4-38.1 | 20.9 | 20.2-21.6 | 11.5 | 10.9-12.2 | 8.2 | 7.5-8.9 | |
| 75+ | 12,511 | 18.3 | 17.6-19.1 | 10.4 | 9.8-11.0 | 6.1 | 5.6-6.7 | 4.0 | 3.4-4.7 | |
aThe cohort analysis of survival rates was utilized for calculating the survival estimates presented in this table. Long-term cohort-based survival estimates reflect the survival experience of individuals diagnosed over the time period, and they may not necessarily reflect the long-term survival outlook of newly diagnosed cases.
bRates are an estimate of the percentage of patients alive at one, two, five, and ten years, respectively. Rates were not presented for categories with 50 or fewer cases and were suppressed for rates where fewer than 16 cases were surviving within a category.
cEstimated by CBTRUS using Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2017 Sub (2000-2015) <Katrina/Rita Population Adjustment> - Linked To County Attributes - Total U.S., 1969-2016 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 2018, based on the November 2017 submission.
dTotal number of case that occurred within the SEER registries between 2000 and 2015.
eTotal includes histologies not listed in this table.
-- Counts and rates are not presented for categories with 50 or fewer cases and were suppressed for rates where fewer than 16 cases were surviving within a category. The suppressed cases are included in the counts and rates for totals.
Abbreviation: CBTRUS, Central Brain Tumor Registry of the United States; SEER, Survival, Epidemiology, and End Results; CI, confidence interval; NOS, not otherwise specified