Table 7.

Five-Year Total, Annual Average Total^a, and Average Annual Age-Adjusted Incidence Rates^b with 95% Confidence Intervals for Brain and Other Central Nervous System Tumors by Site^c and Sex, CBTRUS Statistical Report: NPCR and SEER, 2011-2015

Site (ICD-O-3 Code)	Total					Male						Female
	5-Year Total	Annual Average	% of All Tumors	Rate	95% CI	5-Year Total	Annual Average	% Malignant	% Non-Malignant	Rate	95% CI	5-Year Total	Annual Average	% Malignant	% Non-Malignant	Rate	95% CI
Frontal, temporal, parietal, and occipital lobes of the brain (C71.1-C71.4)	73,581	14,716	18.7%	4.27	4.24-4.30	40,956	8,191	91.4%	8.6%	5.04	4.99-5.09	32,625	6,525	87.9%	12.1%	3.60	3.56-3.64
Frontal lobe (C71.1)	32,053	6,411	8.2%	1.88	1.86-1.90	17,064	3,413	92.0%	8.0%	2.11	2.08-2.15	14,989	2,998	88.8%	11.2%	1.67	1.65-1.70
Temporal lobe (C71.2)	23,775	4,755	6.0%	1.37	1.35-1.39	14,155	2,831	90.8%	9.2%	1.73	1.70-1.76	9,620	1,924	87.0%	13.0%	1.06	1.04-1.08
Parietal lobe (C71.3)	13,947	2,789	3.5%	0.80	0.78-0.81	7,603	1,521	92.5%	7.5%	0.93	0.91-0.95	6,344	1,269	88.7%	11.3%	0.68	0.67-0.70
Occipital lobe (C71.4)	3,806	761	1.0%	0.22	0.21-0.23	2,134	427	87.0%	13.0%	0.26	0.25-0.28	1,672	334	81.7%	18.3%	0.18	0.17-0.19
Cerebrum (C71.0)	6,839	1,368	1.7%	0.41	0.40-0.42	3,707	741	83.7%	16.3%	0.46	0.45-0.48	3,132	626	79.9%	20.1%	0.36	0.35-0.38
Ventricle (C71.5)	4,106	821	1.0%	0.26	0.25-0.27	2,196	439	43.9%	56.1%	0.28	0.27-0.29	1,910	382	40.7%	59.3%	0.24	0.23-0.25
Cerebellum (C71.6)	8,710	1,742	2.2%	0.55	0.54-0.57	4,589	918	62.5%	37.5%	0.60	0.58-0.61	4,121	824	55.8%	44.2%	0.52	0.50-0.53
Brain stem (C71.7)	6,012	1,202	1.5%	0.39	0.38-0.40	3,241	648	75.8%	24.2%	0.42	0.41-0.44	2,771	554	78.1%	21.9%	0.36	0.35-0.37
Other brain (C71.8-C71.9)	33,817	6,763	8.6%	1.96	1.94-1.99	17,676	3,535	83.1%	16.9%	2.21	2.18-2.25	16,141	3,228	77.9%	22.1%	1.75	1.73-1.78
Spinal cord and cauda equina (C72.0-C72.1)	12,333	2,467	3.1%	0.75	0.73-0.86	6,390	1,278	29.2%	70.8%	0.80	0.78-0.82	5,943	1,189	27.6%	72.4%	0.70	0.68-0.72
Cranial nerves (C72.2-C72.5)	27,656	5,531	7.0%	1.60	1.58-1.62	13,028	2,606	5.9%	94.1%	1.57	1.55-1.60	14,628	2,926	5.4%	94.6%	1.64	1.61-1.67
Other nervous system (C72.8-C72.9)	2,455	491	0.6%	0.15	0.14-0.15	1,261	252	56.7%	43.3%	0.16	0.15-0.17	1,194	239	50.8%	49.2%	0.14	0.13-0.14
Meninges (cerebral and spinal) (C70.0-C70.9)	146,157	29,231	37.2%	8.35	8.30-8.39	39,533	7,907	2.4%	97.6%	5.00	4.95-5.05	106,624	21,325	1.1%	98.9%	11.28	11.21-11.35
Pituitary and craniopharyngeal duct (C75.1-C75.2)	68,838	13,768	17.5%	4.19	4.16-4.22	31,177	6,235	0.9%	99.1%	3.87	3.83-3.91	37,661	7,532	0.6%	99.4%	4.59	4.54-4.64
Pineal (C75.3)	1,750	350	0.4%	0.11	0.11-0.12	973	195	73.7%	26.3%	0.13	0.12-0.13	777	155	41.2%	58.8%	0.10	0.09-0.11
Olfactory tumors of the nasal cavity (C30.0c)	728	146	0.2%	0.04	0.04-0.05	421	84	-	-	0.05	0.05-0.06	307	61	-	-	0.04	0.03-0.04
TOTAL	392,982	78,596	100.0%	23.03	22.96-23.11	165,148	33,030	40.7%	59.3%	20.59	20.49-20.69	227,834	45,567	23.7%	76.3%	24.31	25.20-25.42

^aAnnual average cases are calculated by dividing the five-year total by five.

^bRates are per 100,000 and are age-adjusted to the 2000 US standard population.

^cThe sites referred to in this table are loosely based on the categories and site codes defined in the SEER site/histology validation list.

^dICD-O-3 histology codes 9522-9523 only.

Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval