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. 2018 Sep 10;38:25. doi: 10.1186/s41232-018-0083-8

Fig. 1.

Fig. 1

Schematic model of early vascular development. Endothelial cells are derived from mesodermal precursors: angioblasts and hemangioblasts. They form vascular networks by undergoing morphological changes. Possible transcription factors (red) and signaling molecules (green) controlling each process are shown. During early vascular development, hematopoietic lineages arise from hemangioblasts or hemogenic endothelium