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. 2018 Sep 10;16:168. doi: 10.1186/s12916-018-1134-3

Table 3.

Risk-benefit ratios for rotavirus vaccination

Induced IS: prevented fatal cases Induced IS: prevented hospitalized cases Induced complicated IS: prevented fatal cases Induced complicated IS: prevented hospitalized cases
All children
 Targeted vaccination 1:21 (1:12–1:33) 1:1707 (1:1494–1:1920) 1:445 (1:244–1:691) 1:35,564 (1:31,126–1:39,995)
 Universal vaccination 1:1.8 (1:1.0–1:2.8) 1:685 (1:603–1:767) 1:37 (1:20–1:59) 1:14,267 (1:12,566–1:15,974)
Targeted group
 Targeted vaccination 1:21 (1:12–1:33) 1:1707 (1:1494–1:1920) 1:445 (1:244–1:691) 1:35,564 (1:31,126–1:39,995)
 Universal vaccination 1:22 (1:12–1:34) 1:2012 (1:1773–1:2252) 1:455 (1:250–1:706) 1:41,913 (1:36,942–1:46,921)
Healthy children
 Targeted vaccination NA NA NA NA
 Universal vaccination 1:0.05 (1:0.00–1:0.16) 1:571 (1:503–1:639) 1:1.0 (1:0.03–1:3.24) 1:11,896 (1:10,475–1:13,319)