Table 3.
Risk-benefit ratios for rotavirus vaccination
| Induced IS: prevented fatal cases | Induced IS: prevented hospitalized cases | Induced complicated IS: prevented fatal cases | Induced complicated IS: prevented hospitalized cases | |
|---|---|---|---|---|
| All children | ||||
| Targeted vaccination | 1:21 (1:12–1:33) | 1:1707 (1:1494–1:1920) | 1:445 (1:244–1:691) | 1:35,564 (1:31,126–1:39,995) |
| Universal vaccination | 1:1.8 (1:1.0–1:2.8) | 1:685 (1:603–1:767) | 1:37 (1:20–1:59) | 1:14,267 (1:12,566–1:15,974) |
| Targeted group | ||||
| Targeted vaccination | 1:21 (1:12–1:33) | 1:1707 (1:1494–1:1920) | 1:445 (1:244–1:691) | 1:35,564 (1:31,126–1:39,995) |
| Universal vaccination | 1:22 (1:12–1:34) | 1:2012 (1:1773–1:2252) | 1:455 (1:250–1:706) | 1:41,913 (1:36,942–1:46,921) |
| Healthy children | ||||
| Targeted vaccination | NA | NA | NA | NA |
| Universal vaccination | 1:0.05 (1:0.00–1:0.16) | 1:571 (1:503–1:639) | 1:1.0 (1:0.03–1:3.24) | 1:11,896 (1:10,475–1:13,319) |