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. Author manuscript; available in PMC: 2018 Sep 10.
Published in final edited form as: J Med Chem. 2018 Aug 13;61(16):7116–7130. doi: 10.1021/acs.jmedchem.8b00253

Figure 1.

Figure 1.

(A) Chemical synthesis of compounds 1−10 using the Cbz-Lys-AMC backbone. (B) Synthesis of 2-FBzAHA (12) and precursor 2-NO2BzAHA (13) and radiosynthesis of 2-[18F]BzAHA (14) from the aminohexanoicanilide backbone. (C) Quality-control chromatogram demonstrating matching elution times for both the standard compound, 12 (blue), and the radiofluorinated compound, 14 (2-[18F]BzAHA, red).