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. Author manuscript; available in PMC: 2018 Sep 10.
Published in final edited form as: J Med Chem. 2018 Aug 13;61(16):7116–7130. doi: 10.1021/acs.jmedchem.8b00253

Figure 5.

Figure 5.

(A) PET−CT−MR images at 20 min after iv administration of 2-[18F]BzAHA. (B) PET−CT−MR images at 20 min after iv administration of 2[18F]BzAHA and 50 min after pretreatment with the SIRT1 selective inhibitor, EX-527 (ip; 5 mg/kg). (C) SUV values for the ROI at 20 min after iv administration of 2-[18F]BzAHA with (gray) and without (black) pretreatment with EX-527. Error bars represent standard deviation (n = 2). *P < 0.05.