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. Author manuscript; available in PMC: 2018 Sep 10.
Published in final edited form as: Mol Imaging Biol. 2011 Oct;13(5):853–861. doi: 10.1007/s11307-010-0408-8

Scheme 1.

Scheme 1

Synthetic schemes for preparation of the non-radioactive compound 4-[(3-iodophenyl)amino]-7-[2-{2-(2-[2-{2-(2-fluoroethoxy)-ethoxy}-ethoxy]-ethoxy)-ethoxy}-ethoxy]-quinazoline-6-yl-acrylamide 1. a Synthesis of 1. b Preparation of 7. c Preparation of precursor 9.