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. Author manuscript; available in PMC: 2019 Aug 20.
Published in final edited form as: Chem Res Toxicol. 2018 Jul 30;31(8):697–711. doi: 10.1021/acs.chemrestox.8b00055

Table 1.

POLK Single Nucleotide Polymorphisms Studied

ID amino acid mutation domain tumor site
rs3104729 L21F N-clasp prostate
rs3094258 I39T N-clasp prostate, melanoma
rs148385845 P169T fingers lunga
rs150515841 F192C palm
rs3104717 R219I palm prostate
rsl42203892 E292K palm
rs151251843 R298H palm large intestinea
rs35257416 S423R little finger (PAD) melanoma
rs77612491 Y432S little finger (PAD) melanoma
a

From 1000 genomes.