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. 2017 Apr 21;49(4):e318. doi: 10.1038/emm.2017.15

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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RNA-Seq revealed the upregulation of the glutathione metabolism pathway in ESCC. (a) Scatter plot generated from RNA-Seq data demonstrates that a large number of transcripts were altered in ESCC compared with control. (b) Selected enriched KEGG pathways in ESCC, ordered from top to bottom from highest to lowest P-value. Numbers of transcripts and P-value in each pathway are indicated in the text next to each pathway. (c) Heat map of 16 differentially expressed genes involved in glutathione metabolism.