Table 1.
Participants with complete dose of iPACES™ vs inadequate dose
| Timepoint | Variable | Complete dose (≤2×/wk) |
Inadequate dose (≤2×/wk) |
p-value | ||
|---|---|---|---|---|---|---|
| Ave | SD | Ave | SD | |||
| Demographics | Age | 69.40 | 13.81 | 61.60 | 13.05 | 0.31 |
| Education (years) | 15.80 | 2.39 | 14.80 | 2.28 | 0.45 | |
| MoCA | 24.70 | 3.56 | 23.20 | 4.97 | 0.51 | |
| Pretrial | Color Trails ratio 1/2 | 0.45 | 0.16 | 0.45 | 0.03 | 1.00 |
| Digit Span ratio F/B | 0.65 | 0.17 | 0.69 | 0.21 | 0.70 | |
| Stroop ratio A/C | 0.49 | 0.10 | 0.38 | 0.16 | 0.11 | |
| Word recall (ADAS delayed) | 6.83 | 1.17 | 6.00 | 3.54 | 0.60 | |
| Midtrial (6 weeks) | Color Trails ratio 1/2 | 0.50 | 0.14 | 0.41 | 0.05 | 0.20 |
| Digit Span ratio F/B | 0.71 | 0.24 | 0.67 | 0.18 | 0.84 | |
| Stroop ratio A/C | 0.49 | 0.11 | 0.43 | 0.24 | 0.50 | |
| Word recall (ADAS delayed) | 8.00 | 2.76 | 6.40 | 3.78 | 0.44 | |
| Posttrial (3 months) | Color Trails ratio 1/2 | 0.44 | 0.11 | 0.36 | 0.11 | 0.19 |
| Digit Span ratio F/B | 0.62 | 0.09 | 0.53 | 0.24 | 0.34 | |
| Stroop ratio A/C | 0.53 | 0.12 | 0.41 | 0.14 | 0.10 | |
| Word recall (ADAS delayed) | 8.83 | 0.98 | 6.20 | 3.90 | 0.14 | |
Abbreviations: iPACES, interactive Physical and Cognitive Exercise System; MoCA, Montreal Cognitive Assessment; ADAS, Alzheimer’s Disease Assessment Scale; Ave, average; wk, week.