Table 3.
Treatment | Dose (mg/kg) | Pretreatment timeto tail withdrawal (s) | Post-treatment timeto tail withdrawal (s) | % Inhibition |
---|---|---|---|---|
Control | – | 1.9 ± 0.2 | 1.9 ± 0.3 | – |
D. saxatilis | 100 | 1.9 ± 0.1 | 2.1 ± 0.5b | 1.9 |
200 | 2.0 ± 0.2 | 2.3 ± 0.4b | 2.6 | |
Morphine | 10 | 2.0 ± 0.1 | 7.2 ± 0.7a | 71.4 |
Table showing the effects of pretreatment with Dalbergia saxatilis, morphine or distilled water at intervals of 30 min on tail withdrawal in rats whose tails were dipped in hot water (55.0 ± 0.5 °C). Each value represents mean ± S.E.M or percentage inhibition of pain as compared to control animals, n = 5. Significant at p < 0.05 (ANOVA, Fisher’s PLSD test),
Significant inhibition compared to control given distilled water;
Significantly lower inhibition compared to morphine-treated animals.