Table 6.
Effect of D. saxatilis on formalin test in mice.
| Treatment | Dose (mg/kg) | Total paw-licking time first phase (0-5 min) (s) | % Inhibitionfirst phase | Total paw-licking time second phase (15-30 min) (s) | % Inhibitionsecond phase |
|---|---|---|---|---|---|
| Control | – | 109.0 ± 4.2 | – | 103.4 ± 5.4 | – |
| D. saxatilis | 100 | 100.2 ± 4.9b,c | 4.92b,c | 106.6 ± 4.3b,c | 0b,c |
| 200 | 81.6 ± 4.8a,b | 25.70a,b | 100.3 ± 4.6b,c | 0b,c | |
| Aspirin | 100 | 99.8 ± 4.5b | 4.76b | 64.8 ± 4.6a | 67.33a |
| Morphine | 10 | 22.8 ± 2.5a,c | 81.42a,c | 64.3 ± 3.9a | 66.11a |
Table showing the hindpaw-licking activity of mice injected with formalin after pretreatment with Dalbergia saxatilis, aspirin, morphine or distilled water. Each value represents mean ± S.E.M or percentage inhibition of pain compared to control, n = 5. Significant at p < 0.05 (ANOVA, Fisher’s PLSD test),
a
Significant inhibition compared to control given distilled water;
b
Significantly different inhibition compared to morphine-treated animals;
c
Significantly different inhibition compared to aspirin-treated animals.