Figure 2.

Effects of compounds 1–4, and 7 on nitrite production in LPS-stimulated BV2 microglia (A−E). Cells were pretreated for 3 h with the indicated concentrations of the compounds, then stimulated for 18 h with LPS (1 μg/mL). The concentrations of nitrite were determined using a Griess reaction. Data represent the mean ± S.D. of three experiments. #p < 0.05, as compared with the control group; *p < 0.05, as compared with the group treated with LPS only. Butein was used as the positive control.