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. 2018 Mar 22;56(1):235–244. doi: 10.1080/13880209.2018.1448873

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Inhibition of HER2/neu (erbB2) tyrosine kinase by P. dioica extracts and fractions. Phosphorylation of poly-GluTyr by purified erbB2 intracellular domains was measured by immunoassay with antiphosphotyrosine antibodies. The 50% methanol fraction was the most active with an IC₅₀ of 5.5 μg/mL.