Table 1.

Effects of apigenin, myricetin or their combination on kidney function tests.

Parameters Drugs	Creatinine level (mg/dL)	BUN level (mg/dL)
Control	0.57 ± 0.016	25.5 ± 1.5
Apigenin	0.56 ± 0.32	25.25 ± 1.3
Myricetin	0.48 ± 0.02	22.5 ± 0.71
Apigenin + Myricetin	0.45 ± 0.03	21.37 ± 0.59
Cisplatin	1.6 ± 0.173*	58 ± 1.15*
Cisplatin + Apigenin	0.83 ± 0.03a	41.7 ± 1.1a
Cisplatin + Myricetin	0.77 ± 0.025a	37.2 ± 2.08a
Cisplatin + Apigenin + Myricetin	0.62 ± 0.02a	29.6 ± 0.67a,b,c