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. 2018 Mar 21;56(1):225–234. doi: 10.1080/13880209.2018.1446031

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Response of the crude extract of Rumex acetosa (Ra.Cr) and its fractions on assorted parameters in isolated rat aorta preparations. (A–D) Endothelium-dependent vasorelaxant response of the crude extracts of Rumex acetosa (Ra.Cr); n-hexane (Ra.nHex); ethyl acetate (Ra.EtAc) and chloroform (Ra.Chlor) fractions in aortic rings precontracted with PE (1 µM). (E) Endothelium-dependent contractile and endothelium-independent relaxant effect of the aqueous (Ra.Aq) fraction in aortic rings precontracted with PE (1 mM). (F) The endothelium-independent vasodilator effect of verapamil. (G) The combined vasodilator effect of Ra.Cr, Ra.nHeaxane, Ra.Chlor, Ra.EtAc and Ra.Aq on K⁺ (80 mM)-induced contractions in isolated rat aorta rings. Values shown are mean ± SEM. Five to six determinations.