. 2017 Jul 20;55(1):1972–1983. doi: 10.1080/13880209.2017.1345950

Table 2.

Effect of 10 days daily oral administration of N-acetylcysteine and saponin on nitro-oxidative stress markers in rats with ferrous sulphate-induced hepatotoxicity.

Parameters	Liver GSH content (mg/g wet tissue)	Liver MDA content (nmol/g wet tissue)	Liver NO_x production (μmol/g wet tissue)
Statistical data	(F = 78.97, dF between groups = 3, dF within groups =28)	(F = 18.94, dF between groups = 3, dF within groups =28)	(F = 26.62, dF between groups = 3, dF within groups =28)
Normal control (2% Tween 80, p.o.)	1.03 ± 0.057 (n = 8)	96.09 ± 9.496 (n = 8)	280.00 ± 16.810 (n = 8)
Hepatotoxicity control (FeSO₄, 30 mg/kg, i.p.)	0.31 ± 0.025^a (n = 8)	230.50 ± 17.480^a (n = 8)	589.50 ± 20.070^a (n = 8)
N-Acetylcysteine + Ferrous sulphate	0.83 ± 0.019^ab (n = 8)	137.50 ± 12.950^b (n = 8)	382.00 ± 24.350^ab (n = 8)
Saponin + Ferrous sulphate	0.68 ± 0.022^abc (n = 8)	150.10 ± 10.250^ab (n = 8)	453.30 ± 35.670^ab (n = 8)