Table 3.
Effect of 10 days daily oral administration of N-acetylcysteine and saponin on dyslipidaemia markers in rats with ferrous sulphate-induced hepatotoxicity.
| Parameters | Serum TC (mg/dL) | Serum TG (mg/dL) |
|---|---|---|
| Statistical data | (F = 83.85, dF between groups =3, dF within groups =24) | (F = 98.69, dF between groups =3, dF within groups =23) |
| Normal control (2% Tween 80, p.o.) | 51.2 ± 2.31 (n = 7) | 29.8 ± 1.62 (n = 7) |
| Hepatotoxicity control (FeSO4, 30 mg/kg, i.p.) | 118.5 ± 3.81a (n = 8) | 97.8 ± 4.08a (n = 7) |
| N-Acetylcysteine + Ferrous sulphate | 75.8 ± 2.86ab (n = 7) | 59.5 ± 2.85ab (n = 7) |
| Saponin + Ferrous sulphate | 83.2 ± 3.11ab (n = 6) | 53.1 ± 2.20ab (n = 6) |
aSignificantly different from normal control group at p < 0.05.
bSignificantly different from hepatotoxicity control group at p < 0.05.