Table 4.

Effect of 10 days daily oral administration of N-acetylcysteine and saponin on functional markers in rats with ferrous sulphate-induced hepatotoxicity.

Parameters	Serum albumin (g/dL)	Serum total bilirubin (mg/dL)	Serum direct bilirubin (mg/dL)	Serum indirect bilirubin (mg/dL)
Statistical data	(F = 15.10, dF between groups = 3, dF within groups =26)	(F = 98.06, dF between groups = 3, dF within groups =24)	(F = 77.85, dF between groups = 3, dF within groups =24)	(F = 108.60, dF between groups =3, dF within groups =24)
Normal control (2% Tween 80, p.o.)	5.349 ± 0.2351 (n = 8)	0.304 ± 0.0251 (n = 7)	0.111 ± 0.0098 (n = 7)	0.193 ± 0.0156 (n = 7)
Hepatotoxicity control (FeSO4, 30 mg/kg, i.p.)	2.748 ± 0.2529a (n = 8)	1.847 ± 0.0739a (n = 7)	0.679 ± 0.0310a (n = 7)	1.168 ± 0.0444a (n = 7)
N-Acetylcysteine + Ferrous sulphate	4.538 ± 0.3603b (n = 7)	0.842 ± 0.0478ab (n = 7)	0.296 ± 0.0191ab (n = 7)	0.546 ± 0.0291ab (n = 7)
Saponin + Ferrous sulphate	4.367 ± 0.3151b (n = 7)	1.000 ± 0.0911ab (n = 7)	0.366 ± 0.0381ab (n = 7)	0.634 ± 0.0541ab (n = 7)