Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetics parameters for ChA (n = 6).
| R | T1 | T2 | |
|---|---|---|---|
| t1/2 (h) | 0.911 ± 0.187 | 1.094 ± 0.193 | 1.204 ± 0.309a |
| Cmax (μg/mL) | 2.350 ± 0.483 | 2.332 ± 0.606 | 1.655 ± 0.576a |
| Tmax (h) | 1.861 ± 0.499 | 1.833 ± 0.279 | 1.000 ± 0.459a |
| AUC0-t (μg·h/mL) | 5.591 ± 1.406 | 5.325 ± 1.341 | 3.792 ± 1.794a |
| AUC0-∞ (μg·h/mL) | 6.324 ± 1.853 | 6.074 ± 1.473 | 4.216 ± 1.886a |
| F (%) | 96.0 | 66.7 |
p < 0.05, compared with R, T2 has statistical significance.
