Table 3.

Blood biochemistry of healthy mice treated with the S.e. nigrum spinosum extract at a dose of 800 mg/kg.

	Control	S.e. nigrum spinosum	Ara-C
Glucose (mg/dL)	115.72 ± 16.6	72.27 ± 3.8*	106.33 ± 25.8
Cholesterol (mg/dL)	69.73 ± 13.4	66.07 ± 13.6	68.91 ± 10.9
Triglycerides (mg/dL)	79.27 ± 16.2	88.9 ± 13.6	86.6 ± 22.9
Uric acid (mg/dL)	1.8 ± 0.9	2.1 ± 0.7	3.7 ± 0.6*
Urea (mg/dL)	47.66 ± 6.7	45.81 ± 5.9	44.80 ± 2.0
Creatinine (mg/dL)	0.50 ± 0.1	0.48 ± 0.1	0.56 ± 0.2*
AST (U/L)	120.67 ± 18.6	128.33 ± 16.7	248.00 ± 30.8*
ALT (U/L)	59.00 ± 8.7	59.67 ± 13.5	58.00 ± 3.0
Total bilirubin (mg/dL)	0.35 ± 0.1	0.39 ± 0.1	0.23 ± 0.6*

Serum was used to determine the biochemical parameters of the blood using a clinical automatic biochemical analyzer. The aminotransaminase (AST) and alanine aminotransaminase (ALT) levels were determined. The data are presented as the means ± SDs and representative of 20 mice per treatment.

^*Indicates a significant difference (Tukey’s test, p ≤ 0.05).