Table 4.
Blood count of healthy mice treated with the S.e. nigrum spinosum extract at a dose of 800 mg/kg.
| CONTROL | S.e. nigrum spinosum | ARA-C | |
|---|---|---|---|
| WBC (103/mm3) | 6.40 ± 1.40 | 10.53 ± 2.83* | 6.96 ± 2.23 |
| RBC (106/mm3) | 9.37 ± 0.83 | 9.82 ± 1.37 | 9.57 ± 1.28 |
| Hb (g/dL) | 13.87 ± 1.37 | 14.88 ± 1.02 | 16.05 ± 0.79 |
| Hct (%) | 47.79 ± 5.43 | 49.06 ± 4.55 | 50.08 ± 6.15 |
| HCMC (g/dL) | 31.43 ± 1.78 | 32.70 ± 2.17 | 29.35 ± 2.89 |
| VCM (mm3) | 51.38 ± 3.17 | 51.15 ± 3.33 | 53.56 ± 3.46 |
| HCM (pg) | 16.34 ± 1.18 | 16.10 ± 1.44 | 15.84 ± 0.41 |
| PLT (106/mm3) | 80.54 ± 19.54 | 89.93 ± 21.82 | 147.15 ± 35.71* |
Plasma was used to analyze the total leukocytes (WCBs), total red blood cells (RCBs), hemoglobin (Hb), hematocrit (Hct), mean corpuscular hemoglobin (HCMC), mean corpuscular volume (MCV), platelets (PLTs) and differential counts of lymphocytes, granulocytes and monocytes with an automated hematology MICROS 60 instrument. The data are presented as means ± SDs and are representative of 20 mice per treatment.
*
Indicates a significant difference (Tukey’s test, p ≤ 0.05).