Table 1.
The effect of ethanol extract of L. paracasei subsp. paracasei NTU 101-fermented product on arterial blood pressure in rats with hypertension-induced vascular dementia.
| Feeding time | Arterial blood pressure (mm Hg; mean ± SD, n = 6) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| (Week) | NC | DOCA-salt | NTU101F 0.5 | NTU101F 1.0 | NTU101F 5.0 | |||||
| 0 | 112.0 ± 6.8Aa | 112.4 ± 3.8Ac | 105.7 ± 8.0Ad | 112.2 ± 2.9Ae | 109.2 ± 5.4Ad | |||||
| 2 | 113.4 ± 7.0Aa | 129.7 ± 13.6Ac | 126.4 ± 5.0Ac | 131.9 ± 11.2Ade | 126.7 ± 5.1Ac | |||||
| 4 | 121.1 ± 11.1Aa | 153.9 ± 10.5Ab | 145.5 ± 5.8Abc | 147.1 ± 6.1Acd | 143.6 ± 3.8Abc | |||||
| 6 | 115.9 ± 6.4Ba | 173.2 ± 11.5Aab | 168.4 ± 9.7Aa | 171.0 ± 7.5Aab | 170.0 ± 10.6Aa | |||||
| 8 | 121.5 ± 5.4Ba | 176.1 ± 9.5Aa | 168.7 ± 11.5Aa | 173.8 ± 6.0Aa | 169.7 ± 3.8Aa | |||||
| 10 | 120.2 ± 5.7Ca | 185.0 ± 9.1Aa | 161.9 ± 15.0ABab | 158.4 ± 12.2Babc | 153.7 ± 11.4Bab | |||||
| 12 | 124.1 ± 5.6Ca | 185.1 ± 4.3Aa | 151.0 ± 10.2Bab | 151.2 ± 17.3Bbcd | 142.2 ± 11.5BCbc | |||||
NC: normal control rats; DOCA-salt: rats receiving subcutaneous injection of deoxycorticosterone acetate (DOCA, 25 mg/kg BW/day), and 1.0% NaCl and 0.2% KCl in drinking water; NTU101F 0.5, 1.0, and 5.0: DOCA-salt rats treated with 11, 22, and 110 mg/kg BW/day of ethanol extract of NTU 101-fermented product. Different lowercase letters in the same column and uppercase letters in the same row indicate significant difference (p < 0.001) according to Duncan’s multiple range test.