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. 2017 Mar 6;55(1):1263–1273. doi: 10.1080/13880209.2017.1297838

Figure 3.

Figure 3.

Curcumin suppresses the level of miR-155 in human THP-1 cells. (A) The effect of curcumin on cell viability assay. (B,C) Cells were treated with or without curcumin (5, 10, 15 μM) for 2 h before LPS (200 ng/mL) stimulation for another 4 h, then mRNA levels of cytokines (B) and miR-155, BIC expression (C) were measured. (D) mRNA level of cytokines in miR-155 or negative control mimics transfected cells with the treatment of curcumin (15 μM). The data shown represent the mean values of three independent experiments, and the error bars represent the SEM. (#p < 0.05, ###p < 0.001 vs control; *p < 0.05, **p < 0.01,***p < 0.001 vs LPS alone; ns denotes p > 0.05).