Table 1.
Drug/extract | Dose (mg/kg) | Parasitaemia | % chemosuppression | Mean survival time (days) |
---|---|---|---|---|
Distilled water | 10 ml/kg | 35.75 ± 3.06 | – | 12.75 ± 0.47 |
Extract | 75 | 26.50 ± 1.50b | 25.87 | 17.25 ± 0.75b |
150 | 24.50 ± 2.17b | 31.46 | 17.72 ± 0.85b | |
225 | 20.00 ± 3.74a | 44.05 | 18.25 ± 1.03b | |
Dichloromethane | 150 | 12.25 ± 2.20c | 65.73 | 18.00 ± 0.40b |
Ethyl acetate | 150 | 14.25 ± 1.10b | 60.13 | 17.25 ± 0.47b |
n-Butanol | 150 | 19.50 ± 2.63a | 45.45 | 18.75 ± 0.62b |
Chloroquine | 5 | 9.25 ± 3.06c | 74.12 | 24.25 ± 1.25c |
Values are expressed as mean ± SEM.
Significance relative to control:
p < 0.05;
p < 0.01;
p < 0.001, n = 6.