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. 2017 Apr 14;55(1):1619–1622. doi: 10.1080/13880209.2017.1314513

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© 2017 doterra international.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Top 20 canonical pathways matching the bioactivity profile of clove essential oil (CEO, 0.011% v/v) in gene expression in the HDF3CGF system produced using Ingenuity Pathway Analysis (IPA, Qiagen, www.qiagen.com/ingenuity). Each p-value was calculated using right-tailed Fisher's exact test. The p-value measures the likelihood that the observed association between a specific pathway and the dataset is due to random chance. The smaller p-value (the bigger - ln [p-value], indicated by the black bars) the pathway has, the more significantly it matches the bioactivity of CEO. A ratio, indicated by each grey bar, was calculated by taking the number of genes from the CEO dataset that participate in a canonical pathway, and dividing it by the total number of genes in that pathway. GADD45: growth arrest and DNA-damage-inducible protein 45.