Table 1.

Effect of aqueous-methanolic extract of Ficus carica fruit on various cardiac parameters of isolated rabbit heart.

	Force of contraction (g)		Heart rate (BPM)
Dose	Mean ± SEM	% Change from control	Mean ± SEM	% Change from control
Control	2.83 ± 0.08	0.00	126.0 ± 1.45	0.00
1 pg/mL	3.00 ± 0.11ns	6.0	125.0 ± 0.88ns	0.2
10 pg/mL	2.97 ± 0.12ns	4.9	133.0 ± 1.53*	5.8
100 pg/mL	2.70 ± 0.11ns	4.5	111.0 ± 1.15***	11.6
1 ng/mL	2.63 ± 0.08ns	7.0	96.7 ± 1.45***	23.0
10 ng/mL	2.23 ± 0.08**	21.2	88.6 ± 1.20***	29.3
100 ng/mL	1.93 ± 0.12**	31.8	79.3 ± 1.45***	36.7
1 μg/mL	1.67 ± 0.08***	40.9	71.0 ± 1.53***	43.4
10 μg/mL	2.03 ± 0.14**	28.2	84.0 ± 1.73***	33.0
100 μg/mL	2.63 ± 0.08ns	7.06	90.7 ± 1.20***	27.7
1 mg/mL	3.07 ± 0.14ns	8.4	101.0 ± 1.15***	19.6
10 mg/mL	3.17 ± 0.20ns	11.7	110.0 ± 1.20***	12.1

Values are expressed as means ± SEM (n = 3).

^* p < 0.05).

^** p < 0.01).

^*** p < 0.001. ns: non-significant vs. control.