. 2018 Jun 5;3(6):6097–6103. doi: 10.1021/acsomega.8b00202

Table 2. Summary of Compound Activity^a.

compounds	class	R₁	R₂	vacuolization	cell death	K_d (PIKFYVE) (nM)
2a	1	H₃CH₂CO	CH₃	yes	no	23
2c	1	(H₃C)₂HCO	CH₃	yes	no	51
1a (MOMIPP)	2	H₃CO	CH₃	yes	yes	6.9
2b	2	H₃C(H₂C)₂O	CH₃	yes	yes	6.5
2l	3	H₃CO	COOCH₂CH₃	no	yes	540
2o	N/A	H₃CO	COOH	no	no	46

N/A: not assigned. Compound code numbers were assigned as previously reported.⁷

Table 2. Summary of Compound Activitya.