Table 2.
Differentially expressed genes associated with U-tAs, U-iAs, U-MMAs, and U-DMAs in the non-stratified model (n = 31).
| Gene ID | Gene Name | U-tAs β (p-value) |
U-iAs β (p-value) |
U-MMAsβ(p-value) | U-DMAs β (p-value) |
|---|---|---|---|---|---|
| ICAM5 | Intracellular Adhesion Molecule 5 | 0.417 (0.002) |
-0.314 (0.01) |
- | 0.320 (0.01) |
| CCL7 | C-C Motif Chemokine Ligand 7 | 0.291 (0.03) |
- | - | - |
| HLA-DQAV | Major Histocompatability Complex, Class II, DQAlpha 1 |
0.298 (0.04) |
- | - | - |
| TNFSF11 | Tumor Necrosis Factor Superfamily 11 |
- | -0.373 (0.01) |
- | 0.358 (0.01) |
| IL18RAPa | Interleukin 18 ReceptorAccessory Protein |
- | -0.371 (0.01) |
- | 0.353 (0.02) |
| PLAU | Plasminogen Activator, Urokinase | - | -0.337 (0.02) |
- | 0.335 (0.02) |
| CCL26 | C-C MotifChemokine Ligand 26 | - | -0.335 (0.02) |
- | 0.344 (0.02) |
| AIRE | Autoimmune Regulator | - | -0.342 (0.02) |
- | 0.333 (0.02) |
| NOD2 | Nucleotide Binding Oligomerization Domain Containing 2 |
- | -0.312 (0.02) |
- | 0.315 (0.03) |
| SERPING1a | Serpin Family G Member1 | - | -0.318 (0.03) |
- | 0.291 (0.05) |
| THY1 | Thy-1 Cell Surface Antigen | - | -0.325 (0.03) |
- | 0.322 (0.03) |
| PPARG | Peroxisome ProliferatorActivated Receptor Gamma |
- | -0.329 (0.03) |
- | 0.309 (0.04) |
| HLA-DRB1a | Major Histocompatability Complex, Class II, DR Beta 1 |
- | -0.312 (0.03) |
- | - |
| C7 | Complement Component 7 | - | -0.297 (0.03) |
- | 0.290 (0.04) |
| EGR1a | Early Growth Response 1 | - | -0.302 (0.03) |
- | 0.290 (0.04) |
| C9 | Complement Component 9 | - | -0.289 (0.03) |
- | 0.285 (0.04) |
| CEACAM6 | Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 |
- | -0.303 (0.03) |
- | 0.312 (0.03) |
| MUC1 | Mucin 1, Cell Surface Associated | -0.319 (0.03) |
- | - | |
| IL17A | Interleukin 17A | - | -0.306 (0.04) |
- | 0.289 (0.05) |
| PIGR | Polymeric Immunoglobulin Receptor |
- | -0.317 (0.04) |
- | - |
| GP1BB | Glycoprotein 1b Platelet Beta Subunit |
- | -0.308 (0.04) |
- | 0.311 (0.03) |
| CD1A | CD1a Molecule | - | -0.310 (0.04) |
- | 0.291 (0.05) |
| CTSG | Cathepsin G | - | -0.291 (0.04) |
- | 0.293 (0.04) |
| LAG3 | Lymphocyte Activating 3 | - | -0.291 (0.04) |
- | - |
| IGF2R | Insulin Like Growth Factor 2 Receptor |
- | -0.298 (0.04) |
- | - |
| MMEa | Membrane Metallo-Endopeptidase | - | -0.293 (0.04) |
- | - |
| ITLN2 | Intelectin 2 | - | -0.274 (0.05) |
- | - |
| GBP1a | Guanylate Binding Protein 1 | - | -0.285 (0.05) |
- | - |
| LILRA6 | Leukocyte Immunoglobulin Like Receptor A6 |
- | -0.295 (0.05) |
- | - |
| ICAM1 | Intracellular Adhesion Molecule 1 | - | -0.289 (0.05) |
- | - |
| MX1 | MX Dynamin Like GTPase 1 | - | - | 0.304 (0.04) | - |
Genes identified as differentially expressed are displayed with their associated β- and p-values in their respective multivariable linear regression models.
a
Indicates that differential gene expression is associated with shifts in white blood cell composition.