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. Author manuscript; available in PMC: 2018 Sep 10.
Published in final edited form as: Reprod Toxicol. 2017 Aug 6;73:184–195. doi: 10.1016/j.reprotox.2017.07.023

Table 3.

Top ten enriched gene ontology terms in differentially expressed genes in the non-stratified and sex-stratified models.

Genes Differentially Expressed in the Non-Stratified Model

GOTERM Description # of Genes p-value FDR q-value
GO:0006955 Immune response 18 1.08E-15 1.65E-12
GO:0006952 Defense response 11 2.19E-07 3.26E-04
GO:0002684 Positive regulation of immune
system process
7 7.58E-06 0.011295
GO:0009611 Response to wounding 9 8.18E-06 0.012178
GO:0045087 Innate immune response 6 8.36E-06 0.012451
GO:0050778 Positive regulation of immune
response
6 1.06E-05 0.015844
GO:0002449 Lymphocyte mediated
immunity
5 1.23E-05 0.018253
GO:0002460 Adaptive immune response
based on somatic
recombination of immune
receptors built from
immunoglobulin domains
5 1.79E-05 0.026673
GO:0002250 Adaptive immune response 5 1.79E-05 0.026673
GO:0002443 Leukocyte mediated immunity 5 2.77E-05 0.04132
Genes Differentially Expressed in Women Pregnant with a Male Infant

GOTERM Description # of Genes p-value FDR q-value

GO:0006955 Immune response 160 5.19E-131 9.13E-128
GO:0006952 Defense response 116 2.83E-79 4.98E-76
GO:0006954 Inflammatory response 83 4.50E-66 7.92E-63
GO:0009611 Response to wounding 96 1.93E-62 3.40E-59
GO:0002684 Positive regulation of immune
system process
65 5.57E-53 9.81E-50
GO:0048584 Positive regulation of response
to stimulus
56 1.03E-41 1.81E-38
GO:0050778 Positive regulation of immune
response
46 3.14E-40 5.53E-37
GO:0045087 Innate immune response 41 1.83E-34 3.22E-31
GO:0001775 Cell activation 53 1.43E-33 2.52E-30
GO:0001817 Regulation of cytokine
production
44 5.45E-33 9.59E-30
Genes Differentially Expressed in Women Pregnant with a Female Infant

GOTERM Description # of Genes p-value FDR q-value

GO:0006955 Immune response 6 6.92E-05 0.09

Displays the top ten enriched gene ontologies in the differentially expressed genes in the non-stratified model (n = 31) and sex-stratified models (n = 302, n = 11).