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. Author manuscript; available in PMC: 2018 Sep 10.
Published in final edited form as: Reprod Toxicol. 2017 Aug 6;73:184–195. doi: 10.1016/j.reprotox.2017.07.023

Table 4.

Top ten enriched KEGG Pathways in differentially expressed genes in the non-stratified and sex-stratified models.

Genes Differentially Expressed in the Non-Stratified Model

Pathway ID Description # of Genes p-value FDR q-value
- - - - -
Genes Differentially Expressed in Women Pregnant with a Male Infant

Pathway ID Description # of Genes p-value FDR q-value

hsa04060 Cytokine-cytokine receptor interaction 64 1.16E-31 1.30E-28
hsa04640 Hematopoietic cell lineage 31 3.69E-20 4.15E-17
hsa04620 Toll-like receptor signaling pathway 33 5.37E-20 6.04E-17
hsa04630 Jak-STAT signaling pathway 33 5.42E-14 6.09E-11
hsa04672 Intestinal immune network for IgA production 16 1.12E-09 1.26E-06
hsa04210 Apoptosis 20 3.63E-09 4.08E-06
hsa05332 Graft-versus-host disease 14 4.63E-09 5.20E-06
hsa04514 Cell adhesion molecules (CAMs) 24 8.24E-09 9.26E-06
hsa05330 Allograft rejection 13 1.86E-08 2.09E-05
hsa04610 Complement and coagulation cascades 17 2.64E-08 2.97E-05
Genes Differentially Expressed in Women Pregnant with a Female Infant

Pathway ID Description # of Genes p-value FDR q-value

- - - - -

Displays the top ten enriched KEGG pathways in the differentially expressed genes in the non-stratified model (n = 31) and sex-stratified models (n = 302, n=11).