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. 2018 Sep 10;14(9):e1007458. doi: 10.1371/journal.pgen.1007458

Fig 5. Genetically regulated TNFSF15 controls costimulatory capacity.

Fig 5

(A) CD8-depleted PBMC were stained with proliferation dye eFluor670 and stimulated with 1 μg/mL anti-CD3 with and without 10 μg/mL anti-TNFSF15 for 48 hours. Flow cytometry plots depict cells gated on live, CD4+ cells. (B) CD25+ cells were measured as in (A) in samples from rs6478109 genotyped individuals (GG, n = 8; AA, n = 7). (C) CD25+ divided cells were measured in the same samples as in (B). p values from Mann-Whitney test.