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. 2018 Sep 10;13(9):e0203793. doi: 10.1371/journal.pone.0203793

Table 2. The estimated concentrations in percent [%] of the chamber volume (CV) for all analyzed narcotic gases and both mouse strains at the onset of LORR and LOPR.

NMRI Gas concentration [%] CV
LORR LOPR1)
CO2 20 31.1 58.1
CO2 60 44.3 61.0
CO2 100 57.3 66.2
Iso 2% 1.8 1.9
Iso 5% 3.1 3.5
Sevo 4.8% 4.2 4.6
Sevo 8% 5.6 6.5
C57Bl/6J Gas concentration [%] CV
LORR LOPR1)
CO2 20 30.3 48.0
CO2 60 45.1 55.1
CO2 100 56.6 65.3
Iso 2% 1.5 1.9
Iso 5% 2.7 3.4
Sevo 4.8% 3.7 4.5
Sevo 8% 5.0 6.0

1) Please note that for LOPR this is a rough calculation due to anesthetic gas dilution with ambient air.