Table 2.
Secondary structure assignment of amide I peaks in second-derivative reflection–absorption and attenuated total reflection (ATR) spectra of Aβ40 assemblies
| Assignment | 20% GM1 on POPC |
20% GlcCer on POPC |
Self-assembled |
||||||
|---|---|---|---|---|---|---|---|---|---|
| 15 min |
24 h |
48 h |
72 h |
48 h (ATR) |
15 min |
72 h |
15 min (ATR) |
48 h (ATR) |
|
| Deposited | Oligomer/fibrils | Fibrils | Fibrils | Supernatant | Deposited | Oligomer/fibrils | Aggregates | Aggregates | |
| Parallel β | 1637 | 1635 | |||||||
| Antiparallel β | 1630/1679 | 1631/1676a | 1630/1666 | 1630/1670 | |||||
| Turn | 1664a | 1668a/1691 | 1661/1691 | 1662/1695 | 1695 | 1666a | 1667a/1697 | 1697 | 1697 |
a Weak peaks.